Pharmaceutical Facility Cleaning
We Clean to the Most Important Standards…Yours!
Source One specialized cleaning for pharmaceutical facilities.
You have a lot of important things on your plate. Most important is the development and manufacture of pure, safe and effective pharmaceutical products. You can’t risk particulate and bioburden contamination compromising your operations.
Cleaning and sanitation steps hold the key to achieving great results. That means cleaning done by a company that is ISO- and GMP-certified.
That’s what you get from SourceONE.
We Don’t Have to Tell You, Cleaning is a Big Deal.
Cleaning and sanitation of pharmaceutical equipment and facilities account for almost one-third of all production activities. And with the FDA looking over your shoulder, you’re going to need fully documented procedures (SOP), and documented proof that the procedures have been followed meticulously.
That’s Why We Provide Rigorous Hands-on and Classroom Training for our Pharmaceutical Facility Cleaning Specialists.
At the end of the day, no matter how thorough and detailed your SOP is, it’s up to the people doing the work to ensure that it’s done to your standards, to FDA regulatory standards, with accurate, legible work logs that will stand up to scrutiny.
We place special emphasis on having a certified team that undergoes comprehensive training in clean rooms and controlled environments. Our employees have classroom experience and hands-on instruction before they’re ever allowed to go into a pharmaceutical company. They’re also going to be trained to your specific SOP. You wouldn’t want it any other way, and neither would we.
“We have specialized and highly trained cleaning crews for clean rooms, controlled environments, and laboratories. Rigorous training with regards to our clients’ SOPs.”
John Nigro
SourceONE
You Can Always Tell That You’re Dealing With Pros When You Talk to SourceONE.
We know the questions to ask. We know where the problem areas are. We’ve been at this a while now and when needed, we solve problems. We’re resourceful and innovative. When Covid-19 hit, we developed intensive protocols so that facilities could remain open and do their essential work.
More about our Covid-19 solution
At the beginning of the COVID-19 outbreak in March 2020, SourceONE quickly designed a plan for our client to keep their employees safe and their facility open.
We proposed our Healthy Covid-Cleaning ProtocolsTM program which includes a dedicated SourceONE technician to disinfect high-traffic areas and critical laboratories.
Together, we worked with our client to identify a list of high-touch surfaces and potential high-risk areas. SourceONE performed the day/night disinfection 6 days a week, in 6 different buildings. This included electrostatic spraying in high-risk areas such as conference rooms and bathrooms at night.
The result was a substantial decrease in Covid-19 cases.
Put Our Depth of Cleaning Knowledge, Experience and Expertise to Work at Your Facilities.
Whether you have a small research operation or a large production facility, you can count on SourceONE to deliver ISO and GMP/GLP certified cleaning. Our attention-to-detail and thorough documentation truly set us apart in pharmaceutical facility cleaning.
We can tailor a cleaning schedule to your SOP. We can be your daily go-to or supplement your own team as much as you require.
Pharma Facility Cleaning Consulting
We offer newer facilities and start-ups resources and comprehensive consulting on required cleaning processes and procedures to ensure their compliance and for maintaining proper containment, sanitation, and waste disposal.
Ongoing Maintenance Programs
We develop customized maintenance programs tailored to your specific needs, ensuring consistent cleanliness and compliance throughout your facility.
Cleanroom Maintenance
SourceONE provides secure contamination control from ISO 4-ISO 9, using ISO-compliant and GMP quality programs and environmentally friendly and sustainable solutions.
Microbial Control and Diversity
Cleanrooms are traditionally designed to minimize microbial contamination. However, recent studies have revealed a diverse range of microbes in cleanrooms, challenging the assumption of a completely sterile environment.
While cleaning efforts reduce the abundance of microbes, they do not significantly impact the diversity. Archaea, including survival specialists like bacterial spore formers and halophiles, have been found alive in cleanrooms.
Temperature, Humidity, and Atmospheric Pressure
Cleanrooms must meticulously control temperature, humidity, and atmospheric pressure levels. These factors are critical for maintaining consistency, reliability in test results, and minimize particulate contamination.
Antibiotic Resistance and Cleaning Practices
Stringent cleaning practices correlate with the emergence of antibiotic-resistant microbes. This poses challenges for containment and potential economic losses.
A Closer Look at GMP
The GMP rules are very explicit regarding the requirement to clean and sanitize equipment and the manufacturing facility. Your company’s standard procedures and cleaning records alone are evidence of proper cleaning.
1. Cleaning and Sanitation Procedures
GMP requires the cleaning procedures to be fully documented in written procedures. These procedures are initially validated (shown to be effective) specifically for an item of equipment or an area.
Once validated, the procedures are then published as the SOP and implemented with high levels of attention to detail.
2. Cleaning Validation
All cleaning procedures should be validated (shown to be effective) under specific conditions of use. These conditions of use are specified in the SOP.
Employees cannot deviate from the SOP or alter the conditions of use without risking invalidating the cleaning methods. For example, it would seem logical that adding using a stronger sanitizer than the procedure requires would make cleaning faster or better. This is not always the case as you may alter the properties of the solution (e.g. lowering the pH) thus rendering it less effective.
The relevant GMP rules are to only clean under validated conditions and strictly follow procedures.
3. Cleaning and Sanitation Conditions
The written procedures describe the required conditions under which cleaning is optimal.
These conditions must be followed precisely or you risk unacceptable results. For example, too strong of a solution used in sanitizing could damage the surfaces of counters, tabletops, equipment and accessories. The pH balance has to be accurate or you could end encouraging bacteria growth instead of eliminating it. Also, the type and quality of the water used can impact results.
Your SourceONE team understands all of the variables and dials it all in for best results:
Title: Key Components for Optimal Cleaning Conditions
- Strength of the cleaning or sanitizing agent (e.g., 2.0% v/v)
- The type of water or solvent to be used
- The pH of the cleaning agent
- The temperature of the water to be used
- How much to dismantle equipment before cleaning commences
- The contact or residence time for the sanitizing agent on the surface
- What agents to use to clean off the sanitizing agent
- What standard of water to use in the final rinse (GMP, for example, requires purified water for injection as the final rinse)
4. Cleaning and Sanitation Records
One essential GMP rule is the keeping of detailed cleaning records. Cleaning records prove that cleaning took place and evidence of the cleaning outcomes.
For example, the surfaces are visually clean or the results of rinse water tests.
The records must also identify who did the cleaning and when and must be signed.
For automatic cleaning procedures such as clean in place (CIP), the cycle conditions are usually automatically monitored and the conditions recorded.
Cycle conditions may include the temperature, flow rate, time, concentration of solvent, and solvent agitation time. Often, CIP systems have alarms when something goes wrong.
The completed and signed records should be attached to the records since they provide the only objective evidence that cleaning has occurred.
What Must be Cleaned?
- The facility must be regularly cleaned. Particular emphasis is placed on areas or rooms where product is processed.
- Particular emphasis is placed on effectively cleaning all equipment in contact with the product, and it must be cleaned according to validated and detailed procedures.
- All equipment in processing areas not in contact with the product needs regular cleaning to prevent dust and dirt buildup.
- The inside of the factory should be regularly cleaned, but particular attention should be paid to the processing and storage rooms. The floors, surfaces, benches, walls, and ceilings should undergo cleaning at defined intervals.
- Cleaning and sanitation also apply to any equipment in contact with the product during manufacture, such as production and packaging equipment, transfer lines and tanks, and storage containers and drums.
We Take Documentation Very Seriously…a Case Study.
Good Documentation Practices (GDP) are the measures that collectively and individually ensure documentation, whether paper or electronic, is secure, attributable, legible, traceable, permanent, contemporaneously recorded, original, and accurate.
Compliant documentation builds confidence in the quality assurance system and practice. GDP ensures there is traceability in what is being documented. This process is useful for reviews and investigations. A reduction in assumptions/second guessing around procedures that are carried out by the SourceONE team is also a result of this process. Effective documentation practices provide consistent quality, performance of staff, and specifies clear instructions on what has been accomplished with the controlled environment.
Poor Documentation Practices Include:
- Missing signatures and dates at the time an activity was performed
- Non-uniform date and signature
- Activities performed on one day and signed for on another day.
- Illegible handwriting
- Too many corrections & missing reasoning within corrections
- Spaces being left blank and using white out or other masking devices
One of SourceONE’s Life Sciences clients come to us because of continual issues and lapses in GDP (Good Documentation Practice) including missing entries, improper entries, and corrections.
SourceONE addressed this by providing retraining on how to properly review logbooks. The client’s Quality Assurance team created a GDP tracker where all errors found on client-controlled logbooks and corrections made in logbooks are recorded to increase visibility into site documentation. Together, we created a QR code that supervisors can use to track a procedure to review client logbooks and perform any corrections. The QR code acts as a supplement to training.
Following the implementation, the clients noted a significant reduction in GDP errors.
At SourceONE, our focus is always on ensuring that your established processes are failsafe to keep your site production capable.
Pharmaceutical FAQs
WHAT TYPES OF LIFE SCIENCES FACILITIES DO YOU WORK WITH?
SourceONE focuses on the Life Sciences industry with specific focus on biotechnology, pharmaceutical, and medical device laboratories (R&D) and manufacturing facilities.
WHAT MAKES YOUR LIFE SCIENCES SERVICES DIFFERENT FROM OTHERS IN THE INDUSTRY?
The nature of Life Sciences work creates serious challenges for facility managers due to the need for high standards of cleaning required to combat contamination from bacteria, mold and virus.
HOW DO YOU TAILOR YOUR FACILITY MANAGEMENT SOLUTIONS TO MEET OUR NEEDS?
We begin with an assessment to determine the standards and protocols required to achieve the appropriate level of cleanliness for your specific facility. This includes ISO cleanroom standards and BSL (Biological Safety Levels).
WHAT IS GMP CLEANING?
GMP stands for Good Manufacturing Practices which is a system that consists of processes, procedures and documentation that ensures products are consistently produced and controlled according to set quality standards. Implementing GMP cleaning protocols can help cut down on losses and waste. Overall, it protects both company and consumer from negative safety events.
WHAT TYPE OF TRAINING DO SourceONE GXP TECHNICIANS RECEIVE?
Your SourceONE team undergoes comprehensive training and thorough classroom and hands-on instruction in cleanroom and controlled environment practices, tailored to the unique needs of life science facilities including biotechnology, pharmaceuticals, and medical devices.
WHAT ARE THE CHALLENGES IN GMP/GXP CLEANING?
Biopharma products demand a strict stand against contaminants of all types. Additionally, in the ever-evolving realm of biopharma, where new innovations emerge frequently, GMP cleaning remains the consistent foundation ensuring product and worker safety and efficacy.
WHAT IF I DON’T YET HAVE AN SOP?
If you are launching a new Life Sciences venture and need to develop a cleaning and sanitation SOP, we can provide consulting services that include an audit of your facility and operations. Together we will build a detailed cleaning plan that conforms with all necessary ISO/GMP procedures and protocols, along with Good Documentation Practice log books.
Commercial Janitorial Cleaning Services
San Jose, San Francisco, and Greater South and East Bay Area
We Have Many Cleaning Services To Offer:
Commercial Carpet Cleaning
SourceONE’s commercial carpet cleaning involves the professional maintenance and deep cleaning of carpets in business environments such as offices, hotels, and retail spaces.
Using specialized equipment and cleaning techniques, such as hot water extraction, encapsulation, and dry cleaning, our trained technicians remove dirt, stains, and allergens from carpets, enhancing their appearance and extending their lifespan.
This process of commercial carpet cleaning not only improves the overall aesthetics of the workspace but also promotes a healthier indoor environment by reducing pollutants.
From our extensive experience, regular commercial carpet cleaning ensures a clean, professional look and contributes to a positive impression for clients and employees alike.
Read more here about our commercial carpet cleaning services.
Commercial Carpet Cleaning
SourceONE’s commercial carpet cleaning involves the professional maintenance and deep cleaning of carpets in business environments such as offices, hotels, and retail spaces.
Using specialized equipment and cleaning techniques, such as hot water extraction, encapsulation, and dry cleaning, our trained technicians remove dirt, stains, and allergens from carpets, enhancing their appearance and extending their lifespan.
This process of commercial carpet cleaning not only improves the overall aesthetics of the workspace but also promotes a healthier indoor environment by reducing pollutants.
From our extensive experience, regular commercial carpet cleaning ensures a clean, professional look and contributes to a positive impression for clients and employees alike.
Read more here about our commercial carpet cleaning services.
Cement Floor Cleaning
Our commercial cement floor cleaning services involve the professional maintenance and deep cleaning of cement floors in various business environments, including warehouses, factories, laboratories, cleanrooms, and retail spaces.
Utilizing advanced equipment and techniques such as pressure washing, scrubbing, and sealing, SourceONE’s skilled technicians remove dirt, stains, grease, and other contaminants. This process not only enhances the appearance of the cement floors but also ensures a safer, more hygienic workspace by eliminating slip hazards and prolonging the floor’s durability. Regular commercial cement floor cleaning helps maintain a clean, professional environment, boosting workplace safety and contributing to a positive impression for clients and employees.
Please use this link to learn more about our commercial cement floor cleaning services.
Cleanroom Cleaning Services
SourceONE’s cleanroom cleaning services for biotech and pharmaceutical facilities involve specialized maintenance to ensure the highest standards of cleanliness and contamination control in environments where precision and sterility are paramount.
Our trained technicians utilize advanced techniques and equipment, including HEPA filtration, microfiber materials, and specialized disinfectants, to meticulously clean floors, surfaces, and equipment.
This process adheres to strict regulatory standards, removing particles, microbes, and other contaminants to maintain the integrity of sensitive operations. Regular cleanroom cleaning prevents contamination, ensuring the safety and efficacy of biotechnological research and production.
These services are essential for maintaining compliance, protecting products, and ensuring the overall quality of biotech endeavors.
Follow the link to read more about our cleanroom cleaning services.
Commercial Disinfectant Cleaning
SourceONE’s commercial disinfectant cleaning services provide comprehensive sanitization solutions for various business environments, including offices, healthcare facilities, schools, and retail spaces.
Our expert technicians use hospital-grade disinfectants and advanced cleaning techniques to eliminate viruses, bacteria, and other harmful pathogens from surfaces, high-touch areas, and common spaces.
This thorough process includes disinfecting floors, workstations, restrooms, and communal areas, ensuring a safe and hygienic environment. Regular disinfectant cleaning helps reduce the risk of illness, promotes employee and customer health, and enhances overall workplace safety.
These services are vital for maintaining a clean, professional, and compliant business space, and fostering trust and well-being.
Read more about our commercial disinfectant cleaning services here.
Commercial Janitorial Services
SourceONE’s commercial janitorial cleaning services provide essential cleaning and maintenance solutions for a wide range of businesses, ensuring a clean, organized, and hygienic environment.
Our professional janitorial teams perform routine tasks such as dusting, vacuuming, mopping, restroom sanitation, and regular waste removal, as well as specialized services like window cleaning, carpet care, and floor maintenance. Utilizing high-quality equipment and eco-friendly cleaning products, these services are customized to meet the unique needs of each commercial space, including commercial buildings, offices, schools, healthcare facilities, retail stores, and event spaces.
The benefits of commercial janitorial cleaning services extend beyond aesthetics. A clean and well-maintained workspace boosts employee morale and productivity by creating a pleasant and healthy working environment. Regular cleaning reduces the spread of germs and allergens, leading to fewer sick days and promoting overall well-being. Additionally, a pristine business environment leaves a positive impression on clients and visitors, enhancing the company’s reputation.
Please read more about SourONE’s commercial janitorial cleaning services here.
Day Porter Services
Our day porter services provide essential, ongoing cleaning and maintenance support throughout the business day.
Skilled porters handle various tasks, including cleaning restrooms, replenishing supplies, sanitizing high-touch areas, managing waste, and addressing spills or immediate cleaning needs.
These services ensure a consistently clean, safe, and presentable environment for employees and visitors. Day porters also assist with setting up and breaking down meeting rooms and events, ensuring everything runs smoothly.
By maintaining a high standard of cleanliness and promptly addressing issues as they arise, day porter services enhance workplace efficiency and contribute to a positive, professional atmosphere.
Please read more about our day porter services here.
ESD Floor Maintenance
SourceONE’s ESD (Electrostatic Discharge) floor maintenance services are specialized cleaning and care solutions designed for environments where static electricity control is crucial, such as electronics manufacturing, data centers, and laboratories.
Our trained technicians use specific techniques and products to clean and maintain ESD flooring, ensuring its effectiveness in dissipating static charges.
Regular maintenance includes cleaning, conditioning, and testing the flooring to meet industry standards. Proper ESD floor maintenance prevents static build-up, protecting sensitive equipment and reducing the risk of damage or malfunction.
These services ensure a safe, compliant, and efficient workspace, critical for operations that rely on static control.
Please follow this link to read more about our ESD Floor Maintenance services.
Green Cleaning
SourceONE’s green cleaning services offer environmentally friendly cleaning solutions that prioritize the health and well-being of employees, clients, and the planet.
Utilizing eco-friendly products and sustainable practices, our green cleaning services reduce the use of harmful chemicals and minimize environmental impact.
Our green cleaning involves biodegradable and non-toxic cleaning agents and energy-efficient equipment. These practices ensure a clean and healthy workspace and contribute to a sustainable future.
The benefits of green cleaning services are extensive. For companies, green cleaning enhances our customers’ corporate social responsibility profile and frequently improves their brand image by demonstrating a commitment to sustainability.
Employees benefit from a healthier work environment with reduced exposure to toxins and allergens, leading to fewer sick days and increased productivity.
Additionally, green cleaning practices support environmental conservation by reducing pollution and conserving natural resources. Overall, green cleaning services create a safer, healthier, and more sustainable workplace, fostering well-being and promoting eco-conscious business operations.
To learn more about SourceONE’s green cleaning services, please follow this link.
Hard Floor Care and Finishing
SourceONE’s hard floor care and finishing services provide comprehensive maintenance and enhancement for a variety of hard flooring types, including tile, wood, laminate, and vinyl.
Our professional technicians perform tasks such as deep cleaning, stripping, waxing, buffing, and sealing to restore the floor's appearance and protect it from wear and damage.
These services enhance the durability, shine, and aesthetic appeal of hard floors, ensuring they remain in top condition. Regular hard floor care and finishing extend the lifespan of flooring, maintain a clean and professional environment and create a positive impression for employees and visitors.
Learn more about SourcONE’s hard floor care and finishing services here.
Lab Cleaning Services
SourceONE’s professional lab cleaning services provide specialized cleaning solutions tailored to meet the stringent requirements of laboratory environments.
Our trained technicians are equipped with industry-grade equipment and specialized cleaning agents to ensure the cleanliness, safety, and compliance of lab spaces.
These services entail thorough cleaning of laboratory benches, equipment, fume hoods, and other critical areas to prevent cross-contamination and maintain the integrity of research and experiments.
The benefits to companies are manifold. Firstly, professional lab cleaning services uphold regulatory standards, ensuring compliance with industry regulations and standards.
Secondly, they promote a safe and hygienic working environment, reducing the risk of accidents and contamination.
Learn more here about our professional lab cleaning services
Our Services Fit Into The Following Industries:
Contact SourceONE
SourceONE Building Maintenance, Inc. Corporate Headquarters
2974 Scott Blvd.
Santa Clara, CA 95054
Phone: 408-437-3046